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The Skin Laboratory

Demystify your routine. Search our clinically curated ingredient database to understand safety profiles and optimal layering.

Niacinamide

AKA: Vitamin B3
Safe / Gentle

Primary Benefits

Fades hyperpigmentation, strengthens skin barrier, shrinks appearance of pores, regulates sebum.

Pairs Well With

Retinol, Hyaluronic Acid, Azelaic Acid, Peptides, Ceramides.

Do Not Mix With

Pure L-Ascorbic Acid (Vitamin C) if you have highly sensitive skin (can cause temporary flushing).

Retinol

AKA: Vitamin A
Potent / Use with care

Primary Benefits

Accelerates cell turnover, boosts collagen production, diminishes fine lines, wrinkles, and acne.

Pairs Well With

Ceramides, Hyaluronic Acid, Niacinamide, Peptides (for buffering and repair).

Do Not Mix With

AHA, BHA, Benzoyl Peroxide, Vitamin C in the exact same routine.

Salicylic Acid

AKA: BHA (Beta Hydroxy Acid)
Active Exfoliant

Primary Benefits

Oil-soluble acid that penetrates deep into pores to dissolve dead skin cells and sebum, highly effective for blackheads and acne.

Pairs Well With

Hyaluronic Acid, Ceramides, Niacinamide.

Do Not Mix With

Retinol, Glycolic Acid (AHA), or other strong exfoliants simultaneously.

Hyaluronic Acid

AKA: Sodium Hyaluronate
Very Safe / Hydrating

Primary Benefits

A humectant that draws moisture into the skin, holding 1000x its weight in water to instantly plump fine lines.

Pairs Well With

Literally everything. Used as a hydrating base for all actives.

Do Not Mix With

Nothing. Completely safe universally.

Ascorbic Acid

AKA: Vitamin C
Potent Antioxidant

Primary Benefits

Neutralizes free radicals, brightens hyperpigmentation, and stimulates collagen synthesis.

Pairs Well With

Vitamin E, Ferulic Acid, Sunscreen (SPF).

Do Not Mix With

Retinol, AHA/BHA, Benzoyl Peroxide (can cause severe irritation and destabilize the Vit C).

Azelaic Acid

AKA: Dicarboxylic Acid
Safe / Gentle Active

Primary Benefits

Reduces redness, treats rosacea, kills acne-causing bacteria, and fades stubborn post-acne marks (PIE/PIH).

Pairs Well With

Niacinamide, Hyaluronic Acid, Moisturizers.

Do Not Mix With

Use caution when mixing with strong AHA/BHA exfoliants.

Centella Asiatica

AKA: Cica / Gotu Kola
Soothing / Healing

Primary Benefits

Calms inflammation, speeds up wound healing, and restores compromised skin barriers. Excellent for sensitive skin.

Pairs Well With

All ingredients, especially harsh actives (Retinol/Acids) to buffer irritation.

Do Not Mix With

Nothing. Universally safe.

Ceramides

AKA: Lipids / Sphingolipids
Barrier Repair

Primary Benefits

Naturally occurring lipids that make up 50% of the skin barrier. Prevents transepidermal water loss (TEWL).

Pairs Well With

Retinol, Exfoliating Acids, Cholesterol, Fatty Acids.

Do Not Mix With

Nothing. Essential for healthy skin.

Panthenol

AKA: Pro-Vitamin B5
Soothing / Hydrating

Primary Benefits

Acts as both a humectant (attracts water) and an emollient (seals cracks in skin). Heals redness and micro-tears.

Pairs Well With

Hyaluronic Acid, Ceramides, Centella Asiatica.

Do Not Mix With

Nothing. Extremely gentle.

Glycolic Acid

AKA: AHA (Alpha Hydroxy Acid)
Potent Exfoliant

Primary Benefits

Water-soluble acid that dissolves bonds between dead skin cells on the surface. Evens skin texture and boosts glow.

Pairs Well With

Hyaluronic Acid, Ceramides, Snail Mucin.

Do Not Mix With

Retinol, Vitamin C, Salicylic Acid (BHA) in the same routine.

Lactic Acid

AKA: Gentle AHA
Gentle Exfoliant

Primary Benefits

A larger molecular AHA that exfoliates the surface gently while simultaneously acting as a humectant (hydrating).

Pairs Well With

Hyaluronic Acid, Ceramides.

Do Not Mix With

Retinol, Vitamin C.

Snail Mucin

AKA: Snail Secretion Filtrate
Repairing / Hydrating

Primary Benefits

Packed with glycoproteins and hyaluronic acid. Deeply hydrates, repairs barrier damage, and gives a 'glass skin' glow.

Pairs Well With

Acids, Retinol, Vitamin C (perfect buffer).

Do Not Mix With

Nothing.

Peptides

AKA: Polypeptides / Matrixyl
Anti-Aging / Firming

Primary Benefits

Short chains of amino acids that signal the skin to build more collagen and elastin, firming the skin.

Pairs Well With

Ceramides, Hyaluronic Acid, Retinol.

Do Not Mix With

Direct Acids (AHA/BHA) as low pH can break down the peptide bonds.

Bakuchiol

AKA: Vegan Retinol Alternative
Gentle Anti-Aging

Primary Benefits

Functions similarly to Retinol by boosting cell turnover and collagen, but without the redness, peeling, or sun sensitivity.

Pairs Well With

Squalane, Niacinamide, Vitamin C.

Do Not Mix With

Nothing. It is stable and gentle enough to mix.

Tranexamic Acid

AKA: TXA
Brightening

Primary Benefits

Inhibits melanin synthesis and is highly effective against stubborn melasma and hyperpigmentation.

Pairs Well With

Niacinamide, Alpha Arbutin, Vitamin C.

Do Not Mix With

Safe to mix, but monitor for irritation on highly sensitive skin.

Alpha Arbutin

AKA: Bearberry Extract
Pigment Inhibitor

Primary Benefits

A safe alternative to Hydroquinone. Fades sun spots, age spots, and acne scars safely over time.

Pairs Well With

Vitamin C, Niacinamide, Tranexamic Acid (for maximum brightening).

Do Not Mix With

Nothing.

Benzoyl Peroxide

AKA: BPO
Potent Acne Treatment

Primary Benefits

Delivers oxygen into pores to immediately kill P. acnes bacteria. Reduces severe inflammatory acne.

Pairs Well With

Clindamycin, Hydrating moisturizers like Ceramides to offset severe dryness.

Do Not Mix With

Retinol, Vitamin C, AHA/BHA (will cause extreme dryness, peeling, and chemical burns).

Squalane

AKA: Plant-derived Squalene
Lightweight Oil

Primary Benefits

A highly stable, non-comedogenic oil that mimics skin's natural sebum. Locks in moisture without clogging pores.

Pairs Well With

Retinol, Hyaluronic Acid, Any Active.

Do Not Mix With

Nothing.

Glycerin

AKA: Glycerol
Ultimate Humectant

Primary Benefits

Often overlooked but is the most effective and universally tolerated humectant in skincare. Deeply hydrates.

Pairs Well With

Water, Hyaluronic Acid, Ceramides.

Do Not Mix With

Nothing.

Green Tea Extract

AKA: EGCG
Soothing Antioxidant

Primary Benefits

Reduces sebum (oil) production, calms redness, and provides strong antioxidant defense against UV damage.

Pairs Well With

Sunscreen, Niacinamide, Salicylic Acid (great acne-fighting combo).

Do Not Mix With

Nothing.